Immortalized Human Primary Cardiac Microvascular Endothelial Cells

Description

Human cardiac microvascular endothelial cells (HCMECs) are specialized endothelial cells distributed in the myocardial microvascular network. By regulating coronary microcirculation, myocardial perfusion and vessel-cardiomyocyte crosstalk, they play a core role in research on myocardial ischemia/reperfusion (I/R) injury, heart failure, diabetic cardiomyopathy and cardiac regeneration.

Immortalized Human Cardiac Microvascular Endothelial Cells were transduced with lentivirus carrying the SV40 gene and puromycin resistance. Tests confirmed that the cells are free from bacterial and fungal contamination, exhibit excellent proliferation potential, and can be passaged 10-20 times in vitro.