Description
Hypertrophic scars are composed of a small amount of organized collagen fibers and lack a mucoid matrix. Hypertrophic scars result from deep dermal injury, especially wounds formed after trauma and those with prolonged inflammatory and fibrotic phases. The scar size is limited to the injured area without extending to the surrounding uninjured skin, and the scars can regress spontaneously.
Immortalized Human Proliferative Scar Fibroblasts were transduced with lentivirus carrying the SV40 gene and puromycin resistance. Tests confirmed that the cells are free from bacterial and fungal contamination, exhibit excellent proliferation potential, and can be passaged 10-20 times in vitro.
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