Description
Rat chondrocytes (RCs) are terminally differentiated cells isolated from rat articular cartilage (e.g., knee joint, costal cartilage). They are responsible for synthesizing and maintaining cartilage matrix (e.g., type II collagen, aggrecan) and hold core value in research on osteoarthritis (OA), cartilage injury repair and tissue engineering.
Immortalized Rat Chondrocytes were transduced with lentivirus carrying the SV40 gene and puromycin resistance. Tests confirmed that the cells are free from bacterial and fungal contamination, exhibit excellent proliferation potential, and can be passaged 10-20 times in vitro.
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