Description
Green Fluorescent RKO Cell Line has been developed through stable transfection of RKO cell line with tGFP. This cell line expresses green fluorescent protein gene sequences as free cytoplasmatic proteins. Each vial of cells contains more than 3 million viable cells stably expressing tGFP with G418 resistance gene.
This GFP RKO Cell line is ready to use in cell-based assay applications. This stably transfected clonal cell line provides consistent levels of expression, which helps simplify the interpretation of results. Green Fluorescent RKO Cell Line also allow to stablish in vitro models for High Throughput and High Content Screening.
RKO cells are a human colon cancer cell line useful in research on colorectal cancer.
- They originate from a moderately differentiated colon adenocarcinoma.
- They are distinct due to their wild-type p53 status, which is rare among many cancer cell lines.
- This characteristic makes RKO cells especially useful for investigating p53 function and studying DNA repair mechanisms and apoptosis within colorectal cancer contexts.
With an epithelial-like structure, RKO cells are known for their genetic stability and responsiveness to various genetic and pharmacological interventions. They play a crucial role in studies that examine cancer progression pathways, such as cell cycle control, signal transduction, and metastasis. RKO cells help researchers understand how certain genes and environmental factors influence colorectal cancer and serve as a model for evaluating the effectiveness of anti-cancer treatments.
