Description
Green Fluorescent C2C12 Cell Line has been developed through stable transfection of C2C12 cell line with tGFP. This cell line expresses green fluorescent protein gene sequences as free cytoplasmatic proteins. Each vial of cells contains more than 3 million viable cells stably expressing tGFP with G418 resistance gene.
The fluorescent C2C12 Cell line is ready to use in cell-based assay applications.
- This stably transfected clonal cell line provides consistent levels of expression.
- It helps simplify the interpretation of results.
- It also allow to establish in vitro models for High Throughput and High Content Screening.
Green Fluorescent C2C12 Cell Line are suitable for both, in vitro and in vivo experimentation.
The C2C12 cell line, a subclone developed by H. Blau and colleagues from the original mouse myoblast line created by D. Yaffe and O. Saxel, differentiates quickly into contractile myotubes and synthesizes typical muscle proteins. When exposed to bone morphogenetic protein 2 (BMP-2), the differentiation pathway shifts from myoblastic to osteoblastic.
