Description
Arginine Vasopressin Receptor 1A Cell Line contains HEK293 cells stably expressing human Arginine Vasopressin receptor 1A with no tag. The AVPR1A cell line has been designed to assay compounds or analyze their capability to modulate Arginine Vasopressin receptor 1A. When the agonist binds to AVPR1A a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (Ca). This cell line has been validated measuring Calcium increase in the cytosol. The high reproducibility of this assay allows monitoring AVPR1A activation process in High Throughput Screening.
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