5-HT2A Serotonin Receptor Cell Line

$7,625.00

Size: 2 vials, 3 x 10^6 cells/ vial

Description

5-HT2A Serotonin Receptor Cell Line contains U2OS cells stably expressing 5-HT2A Receptor with no tag. HiTSeeker Cell lines proliferate in vitro maintaining GPCR expression following the cell culture manual. The 5-HT2A Serotonin Receptor Cell Line allows to assay compounds, or analyze their capability to modulate 5-HT2A receptor. When a ligand binds to the 5-HT2A receptor, it activates a G protein, which in turn, triggers a cellular response mediated by calcium. This cell line has been validated measuring calcium concentration changes in the cytosol upon activation with 5-HT. The high reproducibility of this assay allows monitoring 5-HT2A Receptor activation process in High Throughput Screening.

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5-HT2A Serotonin Receptor Cell Line