Working with its specialized partner Kylin Labs, Cells Online offers the following list of CNS-focused in vivo and in vitro R&D services for related drug discovery and development. You’re also welcome to inquiry for any CNS related R&D services that you don’t find from the following list:
In vivo pharmacological and pharmacodynamic studies
- Depression animal models
- Anxiety animal models
- Parkinson’s disease animal models
- Alzheimer’s disease animal models
- Pain animal models
- Stroke animal models
In vitro biological studies
- lon channel pharmacodynamic screening
- GPCR receptor efficacy screening
- Transporter/ kinase screening
- In vitro modeling of stem cells and organoids
- Neuropharmacology and pathology
Pharmacokinetics
- In vitro metabolic stability
- In vivo ADME experiments
- In vitro P-gp/ BCRP substrate investigation system
- In vivo SOA rat/mouse model
CNS safety pharmacology
- Evaluation of gait/ coordination anomalies: FOB/ Modified Irwin
- Neuropsychiatric symptom analysis: seizure evaluations of seizure, cognitive dysfunction and sleep disorder
- Evaluation of non-clinical drug dependence
- Evaluation of peripheral nerve conduction
Example Data
- Parkinson’s Disease
- Alzheimers’ Disease